Synonyms:CK Fractionation; CK Isoenzymes, CPK Isoenzymes, Creatine Phosphokinase Isoenzymes
Why It Is Done
When the total CPK level is elevated, isoenzyme testing can help differentiate the source of the damaged tissue. Detect injury to brain and lungs Following a heart attack, used to detect damage to heart muscle Injury or stress to skeletal muscle
Test Overview
CPK isoenzymes test measures the different forms of creatine phosphokinaseCPK is an enzyme found predominantly in the heart, brain, and skeletal muscle. CPK is composed of 3 isoenzymes that differ slightly in structure:
CPK-1 (also called CPK-BB) is concentrated in the brain and lungs. CPK-2 (also called CPK-MB) is found mostly in the heart CPK-3 (also called CPK-MM) is found mostly in skeletal muscle
How To Prepare
No special preparation required