Synonyms: Indirect Antiglobulin Test; Indirect Coombs'

Why It Is Done

Done to find antibodies against red blood cells.
Commonly done to detect antibodies in a recipient's or donor's blood prior to a transfusion.
Detect antibodies during pregnancy.

Test Overview

Antibodies are proteins produced by the immune system. Normally, antibodies bind to foreign substances, such as bacteria and viruses, causing them to be destroyed. Certain conditions can result in the production of antibodies against red blood cells.

The indirect Coombs' test checks for antibodies against red blood cells circulating in your blood but not attached to your red blood cells.

How To Prepare

No special preparation is necessary.