Synonyms: Hb A1c, MBG ; Hb A1c With MBG Estimation

Why is it Done

Clinically, hemoglobin A1c values are used most frequently to assess glucose control in insulin-dependent diabetics whose glucose levels are very labile and in whom single blood glucose measurements may not accurately reflect the level of control present over the preceding few weeks.

Test Overview

Hemoglobin A1c measurements are of less value in stable diabetics, because urine and blood glucose determinations provide simple, economic, and reliable means for assessing glycemic control. In these patients, fasting glucose concentrations are fairly consistent from day to day and there is a significant correlation between hemoglobin A1c and single fasting glucose levels. Although measurement of hemoglobin A1c may provide a unique means of evaluating control in diabetics who have wide fluctuations in blood glucose levels, it is not a substitute for urine and blood glucose levels that are used to regulate insulin dose. Hemoglobin A1c measurements are less sensitive in detecting what is now defined as diabetes than is the GTT.

How to Prepare:

No special preparation is necessary